Developed with JPI Oceans members and co-created with stakeholders, the Strategy Framework 2021-2025 provides a coherent setting for the coming years for efficient and impactful pan-European research and innovation, in support of healthy and productive seas and ocean. The 12 thematic areas of the Strategy Framework are arranged in a continuous framing of ocean requirements with three interconnected priority areas for a resilient ocean; (1) Ocean Health, (2) Ocean Productivity, and (3) Ocean Stewardship & Governance, and the three development ambitions committing to sustainability, blue economy and responsibility.